Platelets are an essential component needed by the body for coagulation and blood clotting. Platelets work along with white and red blood cells for the regulation and normal functioning of blood within our bodies.

These blood cells each have their own functions as well as lifespans.

Among the three, platelets are the smallest yet most important factor in the clotting of blood. If platelets aren’t properly regulated, such as not being renewed at normal healthy intervals, then a blood disorder or dysfunction might occur.

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A platelet’s general lifespan is about 10 days.

The normal platelet count within the human body will range from 150,000 to 450,000 per microliter of blood.

The platelet count will vary in different organs and locations within the body. In the case of certain medical conditions, platelet counts may either decrease or increase in the blood.

Also Read: Can Platelet Counts Fluctuate?

One of the most common platelet count changes is when level drop below normal. This is known as thrombocytopenia.

If this condition occurs, medical attention should be sought immediately, due to bleeding risks. Moreover, this condition can also trigger other diseases that may be idle in the body. In order to deal with a low platelet count, maintaining a balanced diet is of utmost importance.

On the other end of the spectrum, an increase in platelets is a specific condition known as thrombocytosis.

The lifespan of the body’s platelets may depend on things that we do and experience in life. Here are the factors that contribute to our body’s platelet count.


One of the most prevalent factors in determining platelet lifespan is your genetic history; it has been discovered that the platelet count found in human blood is deeply rooted in our genes.

The lifespan of our platelets are also rooted in the way that our ancestors and we live our lives.

Research shows that our lifestyle heavily influences our genes and heredity. Although the general lifespan for platelets is 10 days, our genes can either decrease or increase this amount.


Another primary factor that affects the lifespan of your platelets is your age. This not only serves as a factor in determining platelet lifespan, but also platelet count.

As our body ages, the capacity and regulation of the body system is reduced, affecting the formation and growth of platelets in our blood. As we age, the body’s ability to hold the average 10-day platelet lifespan drastically decreases.

Sialic acid

Other factors, such as sialic acid, also plays a crucial role in the regulation of platelet lifespan within our blood. Among the average platelet cycle of 7 to 10 days, sialic acid can help regulate platelet lifespan to a great extent.

Galatactose, which helps in determining sialic acid presence, can rapidly alter or change a platelet’s lifespan. While these functionalities are still being studied, they are known to play a big role in platelet lifespan.


Humans can have various medical conditions that have an effect on platelets.

When enough platelets are not produced to keep up with the balance of normal platelets death, the body suffers from thrombocytopenia.

In this condition, the platelet count becomes very low, resulting in a medical disorder than can lead to some serious conditions. Other than diseases, pregnancy can lead to a lower platelet count, but the average lifespan will not be affected.


A person’s diet regime and food habits are another factor that contributes to platelet count and lifespan.

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Whole grains, foods that are high in zinc, and green leafy vegetables can all increase platelet count and keep them healthy.

Prolonged intake of medicine

It is widely known that medicines such as pain killers, may ease pain in the moment, but they can have certain long-term effects on the blood.

Certain medicines can have a negative impact on the body’s organs and blood, especially if they are not carefully monitored. The blood’s composition can become imbalanced, not only affecting platelets, but can also lead to organ failure.

Bone marrow

Platelets are actually produced in the bone marrow, so naturally, any disorder that affects the bone marrow, will probably decrease platelet lifespan.

In cases of acute medical disorders such as certain cancers and leukemia, bone marrow is involved, and so is platelet lifespan and count.

Blood transfusion

Conditions that result from improper transfusion of blood is another common influence on the production and regulation of platelet lifespan.

Additionally, blood transfusion may be performed in the case of blood-related disorders or acute injury, but since foreign blood is being infused, the body can react and cause changes in platelet lifespan.

Congenital thrombocytopenia

In the case of a platelet-related medical disorder, such as congenital thrombocytopenia, the platelet count can become lower than its normal range. In the presence of this condition, the platelet count can even drop to a range of 100,000 per microliter of blood.

When this happens, the body will fail to maintain the usual platelet life circulation rates of 7 to 10 days, decreasing lifespan to 5 days or less.

Abnormal cell accumulation

In any area of the body in which cells are abnormally accumulated, platelet life cycle and count can be potentially impaired.

This accumulation is most common in and around the bone marrow, which makes the lifespan of platelet lower.

Platelets are one of the most vital components of the human body, where any abnormal changes can lead to undesirable and even dangerous results. If you are worried about your platelet count or their life cycle, request a blood test from your doctor and talk about the potential risks associated with an abnormal platelet count.



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